The photocatalytic epoxidation of propylene (PR) with molecular oxygen was carried out in a fluidized-bed reactor with several Bi2WO6-based materials under UV-A illumination. Three different photocatalysts were tested: one of single Bi2WO6 and two of coupled Bi2WO6-TiO2 heterostructures, thus showing that a mixed system of Bi2WO6 with commercial TiO2 Degussa-P25 leads to the best combination of conversion and PO selectivity. Then, direct support on glass spheres and silica gel was made, being a good alternative for improving the Bi2WO6 performance. Additionally, several reaction conditions of temperature and PR to O-2 feed ratio were studied.